Saturday, March 31, 2012

Carnosine and lifestyle changes inhibit telomere shortening

by: John Phillip

Scientists have understood the basic mechanism of telomeres, the small zipper-like capsules that bind our DNA genetic material and enable precise cellular reproduction, for more than a decade now. As each cell replicates, the telomere shortens and the potential life-cycle of the cell diminishes slightly until there is no more telomere and cell death ensues. Researchers publishing in the journal Arteriosclerosis, Thrombosis, and Vascular Biology have found that telomere shortening accurately predicts the risk of developing heart disease, suffering a heart attack and early death from all causes.

Smoking and obesity cause systemic inflammation and are a direct cause of telomere shortening. In addition to improving diet and lifestyle risk factors, carnosine supplementation is emerging as an important nutrient that can block telomere shortening and reduce aging effects to increase lifespan (http://www.dreddyclinic.com/findinformation/ww/obesity.php).

Researchers from The University of Copenhagen in Denmark examined the DNA of 20,000 Danes to analyze their specific telomere length, an established measurement of cellular aging. The participants were followed for a period of nineteen years and the results demonstrated that when the telomere length was short, the risk of heart attack and early death was increased by 50 and 25 percent, respectively. Read more...

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